Publications

2011
Safinya CR, Raviv U, Needleman DJ, Zidovska A, Choi MC, Ojeda-Lopez MA, Ewert KK, Li Y, Miller HP, Quispe J, et al. Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids. Advanced Materials. 2011;23 :2260–2270. Download Paper
2010
Needleman DJ, Farhadifar R. Mitosis: Taking the Measure of Spindle Length. Current Biology. 2010;20 :R359–R360. Download Paper
Brugués J, Needleman DJ. Nonequilibrium fluctuations in metaphase spindles: Polarized light microscopy, image registration, and correlation functions, in OPTO. International Society for Optics and Photonics ; 2010 :76180L–76180L. Download Paper
Mirny LA, Needleman DJ. Quantitative characterization of filament dynamics by single-molecule lifetime measurements. Methods in cell biology. 2010;95 :582–600. Download Paper
Nurgaliev D, Gatanov T, Needleman DJ. Automated identification of microtubules in cellular electron tomography. Methods in cell biology. 2010;97 :475–495. Download Paper
Needleman DJ, Groen A, Ohi R, Maresca T, Mirny L, Mitchison T. Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules. Molecular biology of the cell. 2010;21 :323–333. Download Paper
2009
Choi MC, Raviv U, Miller HP, Gaylord MR, Kiris E, Ventimiglia D, Needleman DJ, Kim MW, Wilson L, Feinstein SC, et al. Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study. Biophysical journal. 2009;97 :519–527. Download Paper
Needleman DJ. Cellular allometry: the spindle in development and inheritance. Current Biology. 2009;19 :R846–R847. Download Paper
Schier AF, Needleman D. Developmental biology: Rise of the source–sink model. Nature. 2009;461 :480–481. Download Paper
Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center?. Cell cycle. 2009;8 :1115–1121. Download Paper
Needleman DJ, Xu Y, Mitchison TJ. Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy. Biophysical journal. 2009;96 :5050–5059. Download Paper
Gatlin JC, Matov A, Groen AC, Needleman DJ, Maresca TJ, Danuser G, Mitchison TJ, Salmon ED. Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Current Biology. 2009;19 :287–296. Download Paper
2008
Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Current Biology. 2008;18 :1256–1261. Download Paper
Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. Journal of cell science. 2008;121 :2293–2300. Download Paper
Needleman DJ. Plasmid segregation: is a total understanding within reach?. Current Biology. 2008;18 :R212–R214. Download Paper
2007
Raviv U, Needleman DJ, Ewert KK, Safinya CR. Hierarchical bionanotubes formed by the self assembly of microtubules with cationic membranes or polypeptides. Journal of Applied Crystallography. 2007;40 :s83–s87. Download Paper
Raviv U, Nguyen T, Ghafouri R, Needleman DJ, Li Y, Miller HP, Wilson L, Bruinsma RF, Safinya CR. Microtubule protofilament number is modulated in a stepwise fashion by the charge density of an enveloping layer. Biophysical journal. 2007;92 :278–287. Download Paper
2006
Safinya CR, Ewert K, Ahmad A, Evans HM, Raviv U, Needleman DJ, Lin AJ, Slack NL, George C, Samuel CE. Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications. Philosophical Transactions of the Royal Society of London A: Mathematical, Physical and Engineering Sciences. 2006;364 :2573–2596. Download Paper
Raviv U, Needleman DJ, Safinya CR. Cationic membranes complexed with oppositely charged microtubules: hierarchical self-assembly leading to bio-nanotubes. Journal of Physics: Condensed Matter. 2006;18 :S1271. Download Paper
2005
Raviv U, Needleman DJ, Li Y, Miller HP, Wilson L, Safinya CR. Cationic liposome–microtubule complexes: Pathways to the formation of two-state lipid–protein nanotubes with open or closed ends. Proceedings of the National Academy of Sciences of the United States of America. 2005;102 :11167–11172. Download Paper

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